Institute for medical information - processing, biometry, and epidemiology (IBE)
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Methods in Biostatistics (Boulesteix, Janitza, Probst)

Lectures with tutorials, summer semester 2016

Updates:

DateTopics
02.08.2016 The make-up exam will take place on 13.12.2016 at 10am in the IBE libary.
Please write an email to probst@ibe.med.uni-muenchen.de by 02.12.2016 if you need to take part in the make-up exam.
28.07.2016 The exam results are displayed on the first floor at the Institute of Statistics.
 02.08.201 A review of the exam will take place on Thursday, 02.08.2016, at 15 o'clock in K U1 834 at the IBE.
28.06.2016 The following resources are allowed during the exam: three A4 sheets, double-sided (so 6 pages), handwritten.
09.06.2016

Please write an email to probst@ibe.med.uni-muenchen.de by 10.07.2016 to register for the exam. Please inlude your name, matriculation number, course of study (including examination regulations) for which the exam should count towards, and if applicable your confirmation for an extension of examination time. 

03.05.2016 There will be no lecture on 23.05. The lecture will be postponed to Wednesday, 18.05 from 08:30 to 10:00am (Room HGB A 015).
20.04.2016 The tutorial will now start at 08:30 and end at 10:00am.
04.03.2016 The lecture homepage is online.

  Instructors

Lecture Prof. Dr. Anne-Laure Boulesteix
Tutorial Part A M.Sc. M.Sc. Silke Janitza
Tutorial Part B M.Sc. Philipp Probst

Location and Time

SessionDayTimeLocation
Lecture Monday 09:00 - 12:00 HGB B 015
Tutorial Wednesday (every two weeks) 08:30 - 10:00 HGB A 015

Dates and Topics

DateSessionTopic
11.04.2016 Lecture

A1: Introduction to clinical trials, ethical aspects, structure, bias 

18.04.2016 Lecture A2: Randomization
20.04.2016 Tutorial(Part A) Sheet 1
25.04.2016 Lecture

A3: Study design and analysis of continous outcomes

02.05.2016 Lecture A4: Analysis of binary outcomes
04.05.2016 Tutorial (Part A) Sheet 2
09.05.2016 Lecture A5: Specialized design (Cluster-randomized studies, crossover studies) and meta-analysis
16.05.2016 Cancelled Whitmonday
18.05.2016
(08:30-10:00)
Nur an diesem Termin in HGB A 015
Lecture A6: Subgroup analysis, interactions, multiple testing 
25.05.2016 Tutorial (Part A) Sheet 3
30.05.2016 Lecture A6: Subgroup analysis, interactions, multiple testing
06.06.2016 Lecture A7: Interim analysis, adaptive designs
08.06.2016 Tutorial (Part A) Sheet 4
13.06.2016 Lecture A7: Interim analysis, adaptive designs

B1: Introduction, Design, Examples

20.06.2016 Lecture B2: Binary diagnostics tests
22.06.2016 Tutorial (Part B) Sheet 5
27.06.2016 Lecture B2: Binary diagnostic tests

B3: Continous diagnostic tests (ROC, AUC)

04.07.2016  Lecture B3: Continous diagnostic tests (ROC, AUC)

B4: Verification bias and imperfect reference tests

06.07.2016 Tutorial Sheet 6
13.07.2016 Tutorial Sheet 7

Exam

  • Date: 25.07.2016 at 09:00 o'clock
  • Location: HGB A 125
  • Length: 120 Minutes
  • Allowed references: 3 handwritten DIN A4 sheets and a non-programmable calculator
  • Please bring your student ID and a photo ID to the exam.
  • Exam registriation: Please write an email to probst@ibe.med.uni-muenchen.de by 10.07.2016 to register for the exam. Please inlude your name, matriculation number, course of study (including examination regulations) for which the exam should count towards, and if applicable your confirmation for an extension of examination time.

Literature

  • Part A (Clinical Trials): Matthews JNS (2006). Introduction to randomized controlled clinical trials (2. Auflage), CRC Press.
  • Part B (Diagnostics): Pepe, Margaret Sullivan (2003). The statistical evaluation of medical tests for classification and prediction, Oxford University Press.

Material

The material for the lecture and tutorial can be found under the following link: LSF